Shadow of Doubt is the unique portrait of many people. It represents both men and women, people of all races and all ages. All that changes in the face makes us perplexed, but what remains persistent in it leaves us even more puzzled. Shadow of Doubt is not composed using morphing software, but with the fusion of painting and video. The two media together produce a curious mixture of two different forms of perception, one analogical, and the other digital. As verified by numerous experiments, the two forms of perception depend each on a single brain hemisphere; each hemisphere has, in comparison to the other, a specific functionality. One hemisphere regulates the perception of an object / subject and its meaning if originated by a handmade image (for example the recognition of a landscape drawn on a sheet of paper); the other hemisphere instead regulates the perception of an object / subject and its meaning if originated by a mechanically produced image (for instance the recognition of a landscape from a photographic or video image). In the first case the recognition of the object/subject, and consequently its capacity of communication, happens through an image interpreted by another person; in the second case the recognition, and consequently its capacity of communication, happens through an image only selected by another person, but where the geometric correspondence of all the points that compose the representation is the same that can be observed in reality. The fusion of the two distinct images of reality that might come from the two antithetical readings of the brain hemispheres is the base from which additional information can emerge. In Shadow of Doubt the double information produces the curious feeling that the person represented is always the same but that he or she crosses different stages and forms: from old to young, from man to woman, from adult to child, from a race to another. The somatic traits always remain the same, but the features of the face and all those details that denote age, kind and race, continuously change. In comparison to morphing, which is software able to produce the same effects, but through a totally digital process, the fusion of video with a painted canvas makes the whole image of an extreme realism. The doubt is determined by the impossibility to assimilate such realistic mutation to a circumstance that indeed happens in nature.